Michigan Drug Discovery
Michigan Drug Discovery seeks to support drug discovery projects at the University of Michigan by offering advice and pilot grant funding. Michigan Drug Discovery staff coordindate closely with research cores that focus on screening (Center for Chemical Genomics), Natural Products Discovery, Structural Biology, Medicinal Chemistry and Pharmacokinetics, to advance protects through hit identification, hit-to-lead and lead optimization. We also help to connect faculty with additional internal and external resources to support their projects.
Reach out with questions: we are available to help you figure out the best way to advance your drug discovery project!
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Michigan Drug Discovery Project Grant
Up to $100,000/year for up to two years for collaborative drug discovery research
The Project Grants will advance projects for which compounds active against the intended biological target have been already identified, as well as projects that can benefit from the combined expertise and capabilities of multiple drug discovery experts.
U-M researchers working across all therapeutic areas are eligible for a project grant. Funded projects will be conducted in partnership with Michigan Drug Discovery. Project teams that have already successfully completed a Michigan Drug Discovery supported screening campaign are encouraged to apply for Project Grants. However, prior support through Michigan Drug Discovery is not a prerequisite.
Michigan Drug Discovery Screening Grant
Small molecules: up to $75,000 for use within 12 months
Natural products: up to $100,000 for use within 24 months
DNA-encoded libraries: up to $100,000 for use within 24 months
To be eligible for funding, the proposal must present a clear statement of the scientific hypothesis to be tested, supported by strong target validation or phenotypic data. A prerequisite for funding is a validated screening assay requiring minimal optimization, e.g., translation from 96-well to 384-well format.