Recent News

AI is a Viable Alternative to High Throughput Screening

Michigan researchers participated in a study investigating the potential of virtual screening to identify novel hits for drug discovery.  This work was published in Nature Scientic Reports:  AI is a viable alternative to high throughput screening - a 318-target study...

New Assay for Discovery of Novel RNA Targeting Antibacterials

Antibiotic resistance remains a pressing global concern, with most antibiotics targeting the bacterial ribosome or a limited range of proteins. One class of underexplored antibiotic targets is bacterial riboswitches, structured RNA elements that regulate key...

Accelerating Drug Discovery in Michigan

When University of Michigan (U-M) scientist Isin Cakir, Ph.D. discovered a link between an enzyme called histone deacetylase 6 (HDAC6) and obesity in mice, he knew the next step in his research would be identifying molecules that could potentially block that same...

New immune target offers hope for improved heart disease treatment

A protein believed to be an indicator of cardiovascular disease may actually be what causes the ailment that results in one death every 34 seconds in the U.S, according to a recent study led by University of Michigan researchers. Past research has identified the...

Michigan Drug Discovery’s latest round has technology focus

A new round of funding from Michigan Drug Discovery is bolstering cutting-edge drug discovery technologies at the University of Michigan. The $320,000 in funding reflects MDD’s focus on securing new tools and platforms to support drug discovery research across the...

Michigan Drug Discovery aids new projects to treat obesity, cancer

Michigan Drug Discovery will support four early-stage drug discovery projects to aid work in the Life Sciences Institute’s Center for Chemical Genomics and Natural Products Discovery Core, as well as research in the investigators’ labs. The projects will share...

Michigan Drug Discovery grant program increases researcher support

Michigan Drug Discovery is adding a new grant program to its support for University of Michigan researchers. Project Grants represent the third funding opportunity to be offered by Michigan Drug Discovery, in addition to Screening Grants to support screens conducted...

University of Michigan reports $1.62B in research volume during FY20

The University of Michigan Office of Research has released its Annual Report for Fiscal Year 2020. The research carried out at U-M has led to important advancements in areas ranging from the COVID-19 pandemic to driverless vehicle technology, social justice and carbon...

Great Lakes Discovery RFP open for therapeutic research proposals

Earlier this year, U-M and Deerfield Management announced the creation of Great Lakes Discovery, a new alliance to commercialize U-M therapeutic projects that hold promise in developing potentially life-saving drugs and disease treatments. Through Great Lakes...

Three projects awarded funding from Michigan Drug Discovery

Three innovative drug discovery projects targeting cancer, fungal infection and vision loss are moving forward at the University of Michigan with early-stage funding from Michigan Drug Discovery. “We are excited to help advance these important projects in diverse...

Milken Institute: COVID-19 Treatment and Vaccine Tracker

This information is sourced from: https://milkeninstitute.org/covid-19-tracker. The Milken Institute is currently tracking the development of treatments and vaccines for COVID-19 (coronavirus). This document contains an aggregation of publicly-available information...

Can old drugs take down a new coronavirus?

Lisa M. JarvisMARCH 12, 2020 When any new virus emerges, drug and vaccine developers spring into action, searching for products to stop it in its tracks. Drug discovery campaigns launch, vaccine development efforts ramp up, and everyone mobilizes to get it all into...

Faster drug discovery to hit ‘undruggable’ targets

by the University of MichiganPublished on phys.org Medicines made from coiled protein fragments could provide a new handle on hard-to-treat diseases like cancer, but they are difficult to design. But a new technique, developed at the University of Michigan, could...